000006593 001__ 6593 000006593 005__ 20250425034512.0 000006593 02470 $$ahttps://doi.org/10.1371/journal.pone.0182900$$2doi 000006593 037__ $$aTEXTUAL$$bArticle 000006593 041__ $$aeng 000006593 245__ $$aFactors associated with readmission to the hospital within 30 days in patients with inflammatory bowel disease 000006593 269__ $$a2017-08-24 000006593 336__ $$aArticle 000006593 520__ $$a<p>Background: Management of inpatients with inflammatory bowel disease (IBD) requires increasing resources. We aimed to identify factors associated with hospital readmissions among individuals with IBD.</p> <p>Materials & methods: We collected data from the Healthcare Cost and Utilization Project Nationwide Readmissions Database 2013. We identified individuals with index hospitalizations for IBD. Patient-specific factors, comorbidities and hospitalization characteristics were extracted for the index hospitalization. We performed logistic regression modeling to create adjusted odds ratios (ORs) for 30-day hospital readmission. Subgroup analysis was performed based on disease type and performance of surgery.</p> <p>Results: We analyzed a total of 55,942 index hospital discharges; 3037 patients (7.0%) were readmitted to the hospital within 30 days. Increasing patient age (> 65: OR: 0.45; 95% CI 0.39–0.53) was associated with a decreased risk of readmission, while a diagnosis of Crohn’s disease (OR: 1.09; 95% CI 1.00–1.18) and male sex (OR: 1.16; 95% CI 1.07–1.25) were associated with an increased risk of readmission. The comorbidities of smoking (OR: 1.09; 95% CI 1.00–1.19), anxiety (OR: 1.17; 95% CI 1.01–1.36) and opioid dependence (OR: 1.40; 95% CI 1.06–1.86) were associated with an increased risk of 30-day readmission. Individual hospitalization characteristics and disease complications were significantly associated with readmission. Performance of a surgery during the index admission was associated with a decreased risk of readmission (OR: 0.57; 95% CI 0.33–0.96).</p> <p>Conclusion: Analyzing data from a US publicly available all-payer inpatient healthcare database, we identified patient and hospitalization risk factors associated with 30-day readmission. Identifying patients at high risk for readmission may allow for interventions during or after the index hospitalization to decrease this risk.</p> 000006593 536__ $$oNational Institutes of Health$$cT32DK007074 000006593 536__ $$oNational Institutes of Health$$cK08DK090152 000006593 536__ $$oNational Institutes of Health$$cP30DK42086 000006593 540__ $$a<p>© 2017 Micic et al.</p> <p>This is an open access article distributed under the terms of the <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">Creative Commons Attribution License</a>, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</p> 000006593 542__ $$fCC BY 000006593 594__ $$a<p>Data obtained from the Healthcare Cost and Utilization Project (HCUP) Nationwide Readmissions Database (NRD), sponsored by the Agency of Health Care Research and Quality. This data is available for purchase following completion of a data user agreement available at:&nbsp;<a href="https://www.hcup-us.ahrq.gov/nrdoverview.jsp">https://www.hcup-us.ahrq.gov/nrdoverview.jsp</a>.</p> 000006593 690__ $$aBiological Sciences Division 000006593 691__ $$aMedicine 000006593 7001_ $$1http://orcid.org/0000-0003-2864-1670$$2ORCID$$aMicic, Dejan$$uUniversity of Chicago 000006593 7001_ $$aGaetano, John N.$$uUniversity of Chicago 000006593 7001_ $$aRubin, Jonah N.$$uUniversity of Chicago 000006593 7001_ $$aCohen, Russel D.$$uUniversity of Chicago 000006593 7001_ $$aSakuraba, Atsushi$$uUniversity of Chicago 000006593 7001_ $$aRubin, David T.$$uUniversity of Chicago 000006593 7001_ $$aPekow, Joel$$uUniversity of Chicago 000006593 773__ $$tPLOS ONE 000006593 8564_ $$yArticle$$97b3d63b8-01cc-4a6f-967a-4b70d350e2c8$$s1533239$$uhttps://knowledge.uchicago.edu/record/6593/files/journal.pone.0182900.pdf$$ePublic 000006593 8564_ $$ySupporting information$$9a770d9fc-1c9e-4227-988e-da42b32c2b02$$s716237$$uhttps://knowledge.uchicago.edu/record/6593/files/pone.0182900.zip$$ePublic 000006593 908__ $$aI agree 000006593 909CO $$ooai:uchicago.tind.io:6593$$pGLOBAL_SET 000006593 983__ $$aArticle