@article{TEXTUAL,
      recid = {5878},
      author = {Deji-Abiodun, Oluwafunmilade and Adedokun, Babatunde and  Alexander, Donee and Dutta, Anindita and Ibigbami, Tope and  Olamijulo, John and Adepoju, Dayo and Adekunle, Samuel and  Ojengbede, Oladosu and Olopade, Christopher O.},
      title = {Impact of prenatal maternal psychological distress on  fetal biometric parameters in household air  pollution-exposed Nigerian women},
      journal = {PLOS ONE},
      address = {2022-07-28},
      number = {TEXTUAL},
      abstract = {&lt;p&gt;Rationale&lt;/p&gt; Studies identify prenatal household air  pollution (HAP) exposure and maternal psychological  distress (PMPD) as independent factors contributing to  gestational ill-health and adverse birth outcomes.  &lt;p&gt;Objective&lt;/p&gt; &lt;p&gt;We investigated the impact of PMPD on  fetal biometric parameters (FBP) in HAP-exposed pregnant  Nigerian women.&lt;/p&gt; &lt;p&gt;Methods&lt;/p&gt; &lt;p&gt;The randomized  controlled trial (RCT; ClinicalTrials.gov NCT02394574)  investigated effects of HAP exposure in pregnant Nigerian  women (n = 324), who customarily cooked with polluting  fuels (firewood or kerosene). Half of the women  (intervention group) were given CleanCook ethanol stoves to  use for 156 days during the study. Once a month, all women  were administered an abridged version of the  SF-12v2&lt;sup&gt;TM&lt;/sup&gt; health-related quality of life  questionnaire to assess psychological distress. Using mixed  effects linear regression models, adjusted for relevant  covariates, we analyzed associations between the women’s  exposure to PM&lt;sub&gt;2·5&lt;/sub&gt; (particulate matter with an  aerodynamic diameter&lt;2·5 microns) from HAP, their PMPD  scores, and FBP (ultrasound estimated fetal weight [UEFW],  head circumference [HC], abdominal circumference [AC],  femur length [FL], biparietal diameter [BPD], estimated  gestational age [GA] and intrauterine growth restriction  [IUGR]), and birth anthropometric measures (birth weight  [BW] and birth length [BL]).&lt;/p&gt; &lt;p&gt;Results&lt;/p&gt; &lt;p&gt;PMPD  negatively impacted UEFW, HC, FL, BPD and BL (p&lt;0·05).  Controls (kerosene/firewood users) experienced  significantly higher PMPD compared with ethanol-stove users  (p&lt;0·05). The mediation analysis revealed that the  proportion of the outcome (fetal biometrics, birth  anthropometrics, IUGR and GA), which can be explained via  PMPD by groups (intervention vs. control) after adjusting  for confounding variables was 6·2% (0·062). No significant  correlation was observed between levels of PM&lt;sub&gt;2.5&lt;/sub&gt;  exposure and PMPD scores.&lt;/p&gt; &lt;p&gt;Conclusions&lt;/p&gt; &lt;p&gt;PMPD  was an independent mediator of adverse fetal biometric  parameters in pregnant women, who were exposed to HAP from  burning of firewood/kerosene. Formulating preventative  measures to alleviate maternal distress during pregnancy  and reducing exposure to HAP is important from public  health perspectives.&lt;/p&gt;},
      url = {http://knowledge.uchicago.edu/record/5878},
}