@article{TEXTUAL,
      recid = {5788},
      author = {Aslan, Ibrahim H. and Grant, Jon E. and Chamberlain,  Samuel R.},
      title = {Cognition in adults with borderline personality disorder},
      journal = {CNS Spectrums},
      address = {2023-03-16},
      number = {TEXTUAL},
      abstract = {<p> Objective: Borderline personality disorder (BPD) is a  common and disabling mental health disorder and has  detrimental effects on affected individuals across multiple  domains. We aimed to investigate whether individuals with  BPD differ from control subjects in terms of cognitive  functions, and to see if there is a relationship between  cognitive functions, impulsivity, and BPD symptom  severity.</p> <p>Methods: BPD individuals (n = 26; mean age  = 26.7; 69.2% female) and controls (n = 58; mean age =  25.3; 51.7% female) were enrolled. Intra/Extra-Dimensional  Set Shift (IED) and One Touch Stockings of Cambridge (OTS)  tasks from the Cambridge Neuropsychological Test Automated  Battery (CANTAB) were used to assess cognitive functions.  Barratt Impulsivity Scale-version 11 (BIS−11) was  administered to measure impulsivity and both the Zanarini  Scale for Borderline Personality Disorder self-report and  the clinician-administered versions were used to assess BPD  symptom severity.</p> <p> Results: BPD group showed  significantly impaired cognitive performance on the IED  task versus controls, but there was not a significant  difference in the OTS task. BPD symptom severity was  positively correlated with trait (BIS-11) impulsivity and  no correlation was found between BPD symptom severity and  cognitive functions.</p> <p>Conclusions: This study  suggests people with BPD experience impaired cognitive  flexibility and heightened impulsivity. Only impulsivity  appeared to be directly related to symptom severity,  perhaps indicating that cognitive inflexibility could be a  vulnerability marker. Future research should focus on a  longitudinal approach to extend clinical and theoretical  knowledge in this area.</p>},
      url = {http://knowledge.uchicago.edu/record/5788},
}