@article{TEXTUAL,
      recid = {5500},
      author = {Chu, Francesca and Kappel, Nicole and Akel, Mary and  Press, Valerie G. and Alexander, Jason T. and Volerman,  Anna},
      title = {Validity of the Childhood Asthma Control Test in diverse  populations: A systematic review},
      journal = {Pediatric Pulmonology},
      address = {2023-01-30},
      number = {TEXTUAL},
      abstract = {&lt;p&gt;Purpose: We examined the validity of the Childhood  Asthma Control Test (C-ACT) and identified recommended  thresholds for uncontrolled asthma in children from varying  backgrounds.&lt;/p&gt; &lt;p&gt;Methods: A systematic literature review  was performed utilizing PubMed, Ovid Medline, SCOPUS,  CINAHL, and conference proceedings. Studies were included  if they enrolled children, had a primary outcome of asthma  control, examined test validity or psychometrics, and  utilized the C-ACT. Along with study design and demographic  data, we extracted all outcomes and comparisons used to  validate the C-ACT. We evaluated risk of bias using the  COSMIN Risk of Bias tool. Our protocol was registered with  PROSPERO (CRD42020211119).&lt;/p&gt; &lt;p&gt;Results: Of 4924 records  screened, 28 studies were included. Studies were conducted  internationally and published between 2007 and 2018.  Average number of enrolled participants was 193 (SD = 155,  range = 22-671). Ten studies calculated Cronbach's α (mean  [SD] = 0.78(0.05), range = 0.677-0.83). Thirteen studies  recommended cut-offs for uncontrolled asthma (≤18-≤24).  Nine studies found significant agreement or correlation  between C-ACT and Global Initiative for Asthma  guidelines/physician assessment of asthma control  (correlation coefficients range = 0.219-0.65). Correlation  coefficients between C-ACT and spirometry were &lt;0.6 in five  of six studies that included spirometry. Kappa values for  C-ACT and various spirometry measurements ranged  0.00-0.34.&lt;/p&gt; &lt;p&gt;Conclusions: The C-ACT showed good  internal consistency and mixed levels of agreement and  correlation with various clinical asthma measures.  Recommended cut-offs for asthma control varied and had no  consistent relationship with nationality, race, ethnicity,  or language. Few studies examined cross-cultural validity  and multiple populations remain under-studied.&lt;/p&gt;},
      url = {http://knowledge.uchicago.edu/record/5500},
}