@article{THESIS,
      recid = {3429},
      author = {Taenzler, Ferdinand},
      title = {Application and Development of the Reactions of Oxyallyl  Cations and Synthetic Studies towards Ambiguine Q},
      publisher = {University of Chicago},
      school = {Ph.D.},
      address = {2021-08},
      number = {THESIS},
      pages = {452},
      abstract = {	Cycloadditions have long been held as the premier for  economical constructions in organic synthesis, the use of  which has led to the completion of innumerable total  syntheses and methodologies. Towards this end, the Rawal  group has a long-standing interest in cycloaddition  methodologies and applications in total synthesis. This  thesis details the exploration of a novel approach to  cyclohepta[b] indoles via a [4+3] cycloaddition reaction of  3-alkenyl indoles and stabilized oxyallyl cations. The  transformation was explored fully, and a catalytic,  enantioselective approach via highly acidic  imidodiphosphorimidates (IDPi) was discovered and used to  showcase a general enantioselective [4+3] cycloaddition  reaction of stabilized oxyallyl cations.   Finally, a novel  approach towards the ambiguine alkaloids has been explored,  and significant progress towards amibiguine Q has been  made. Additionally, through the use of our novel [4+3]  cycloaddition methodology, a generalizable route towards  pentacyclic ambiguines has been achieved.   },
      url = {http://knowledge.uchicago.edu/record/3429},
      doi = {https://doi.org/10.6082/uchicago.3429},
}