000001608 001__ 1608 000001608 005__ 20250923113542.0 000001608 0247_ $$2doi$$a10.6082/uchicago.1608 000001608 037__ $$aTHESIS$$bDissertation 000001608 041__ $$aeng 000001608 245__ $$aTransition Metal-Catalyzed Functionalization of C−H and C−C Bonds 000001608 260__ $$bUniversity of Chicago 000001608 269__ $$a2018-08 000001608 300__ $$a989 000001608 336__ $$aDissertation 000001608 502__ $$bPh.D. 000001608 520__ $$aIn this dissertation, the development of several novel organic synthetic methods featuring the functionalization of C−H and C−C bonds was described by using transition metal catalysis, including the Pd-catalyzed β sp3 C−H sulfonyloxylation of alcohols, the Pd-catalyzed γ sp3 C−H arylation of free primary amines, the Pd-catalyzed α-arylation of cyclopentanones, the Rh-catalyzed β sp3 C–H functionalization of ketones, and the Ir-catalyzed C−C cleavage of unstrained ketones driven by aromatization. 000001608 540__ $$a© 2018 Yan Xu 000001608 650__ $$aChemistry 000001608 653__ $$acatalysis 000001608 653__ $$aC-C activation 000001608 653__ $$aC-H activation 000001608 653__ $$atransition metal 000001608 690__ $$aPhysical Sciences Division 000001608 691__ $$aChemistry 000001608 7001_ $$aXu, Yan$$uUniversity of Chicago 000001608 72012 $$aGuangbin Dong 000001608 72014 $$aViresh H. Rawal 000001608 72014 $$aJohn S. Anderson 000001608 8564_ $$92ced7cbb-a855-45bd-9dc1-35dd14a4f1cf$$eEmbargo (2020-08-28)$$s81040484$$uhttps://knowledge.uchicago.edu/record/1608/files/Xu_uchicago_0330D_14513.pdf 000001608 909CO $$ooai:uchicago.tind.io:1608$$pDissertations$$pGLOBAL_SET 000001608 983__ $$aDissertation