000001593 001__ 1593
000001593 005__ 20250829130719.0
000001593 0247_ $$2doi$$a10.6082/uchicago.1593
000001593 041__ $$aeng
000001593 245__ $$aExploring Ontogenetic Relationships Between Form and Function
000001593 260__ $$bUniversity of Chicago
000001593 269__ $$a2018-08
000001593 300__ $$a114
000001593 336__ $$aDissertation
000001593 502__ $$bPh.D.
000001593 520__ $$aAnimals go through significant morphological and physiological change from hatching or birth to adulthood. Despite these transitions, fundamental behaviors such as feeding and locomotion must persist, but their performance may necessitate alternative strategies and structures. Relationships between anatomical structure and behavioral modality have been examined widely across species at the adult life stage, but less attention has been given to how these relationships change through life history. Examining relationships between structure and behavior across life history can provide insight into the evolution of behaviors as well as the functional plasticity that structures may exhibit. In this thesis, I utilize the Mauthner-based startle response in teleost fish and frogs as a model system for examining changes in morphology and behavior through life history. In fish, which have a well-characterized startle, I examine body shape and aspects of neural architecture and relate them back to what we already know about the behavior. In my second chapter I identify an ontogenetic change in body shape that is prevalent across ray-finned fish. In my third chapter, I characterize rostrocaudal regionalization within the larval mechanosensory cell population in zebrafish. Frogs do not have a well-characterized startle repertoire through metamorphosis, so in my fourth chapter I describe how a species of pipid frogs maintains a startle response as it transitions from axial- to limb-based locomotion. In my fifth chapter I discuss the teleost fish and frog systems, and propose experiments that could more directly examine the structure-function relationships that my findings indicate are changing through ontogeny.
000001593 542__ $$fCC BY-NC-ND
000001593 650__ $$aBiology
000001593 650__ $$aBiomechanics
000001593 650__ $$aNeurosciences
000001593 653__ $$ametamorphosis
000001593 653__ $$aontogeny
000001593 653__ $$aRohon-Beard
000001593 653__ $$astartle
000001593 653__ $$aXenopus
000001593 653__ $$azebrafish
000001593 690__ $$aBiological Sciences Division
000001593 690__ $$aPritzker School of Medicine
000001593 691__ $$aIntegrative Biology
000001593 7001_ $$aKatz, Hilary Rose$$uUniversity of Chicago
000001593 72012 $$aMelina E. Hale
000001593 72012 $$aVictoria Prince
000001593 72014 $$aDaniel Margoliash
000001593 72014 $$aMichael Coates
000001593 8564_ $$9c5f119b0-61de-4796-bb73-cdc77a553627$$eEmbargo (2019-08-28)$$s96064759$$uhttps://knowledge.uchicago.edu/record/1593/files/Katz_uchicago_0330D_14467.pdf
000001593 909CO $$ooai:uchicago.tind.io:1593$$pDissertations$$pGLOBAL_SET
000001593 983__ $$aDissertation