@article{TEXTUAL,
      recid = {12682},
      author = {Rubin, John E. and Ng, Vanessa and Chung, Justin and  Salvatierra, Nicolas and Rippon, Brady and Khatib, Diana  and Girardi, Natalia I. and Pryor, Kane O. and Weinberg,  Roniel Y. and Jiang, Silis and Khairallah, Sherif and Mick,  Stephanie L. and Tedore, Tiffany R.},
      title = {Efficacy of parasternal peripheral nerve catheters  &amp;lt;i&amp;gt;versus&amp;lt;/i&amp;gt; no block for median sternotomy: A  single-centre retrospective study},
      journal = {BJA Open},
      address = {2024-06-20},
      number = {TEXTUAL},
      abstract = {&lt;p&gt;Background: Sternal pain after cardiac surgery results  in considerable discomfort. Single-injection parasternal  fascial plane blocks have been shown to reduce pain scores  and opioid consumption during the first 24 h after surgery,  but the efficacy of continuous infusion has not been  evaluated. This retrospective cohort study examined the  effect of a continuous infusion of local anaesthetic  through parasternal catheters on the integrated Pain  Intensity and Opioid Consumption (PIOC) score up to 72  h.&lt;/p&gt; &lt;p&gt;Methods: We performed a retrospective analysis of  patients undergoing cardiac surgery with median sternotomy  at a single academic centre before and after the addition  of parasternal nerve catheters to a standard multimodal  analgesic protocol. Outcomes included PIOC score, total  opioid consumption in oral morphine equivalents, and  time-weighted area under the curve pain scores up to 72 h  after surgery.&lt;/p&gt; &lt;p&gt;Results: Continuous infusion of  ropivacaine 0.1% through parasternal catheters resulted in  a significant reduction in PIOC scores at 24 h (−62, 95%  confidence interval −108 to −16; P&lt;0.01) and 48 h (−50, 95%  CI −97 to −2.2; P=0.04) compared with no block. A  significant reduction in opioid consumption up to 72 h was  the primary factor in reduction of PIOC.&lt;/p&gt;  &lt;p&gt;Conclusions: This study suggests that continuous  infusion of local anaesthetic through parasternal catheters  may be a useful addition to a multimodal analgesic protocol  in patients undergoing cardiac surgery with sternotomy.  Further prospective study is warranted to determine the  full benefits of continuous infusion compared with single  injection or no block.&lt;/p&gt;},
      url = {http://knowledge.uchicago.edu/record/12682},
}