@article{PATENT, recid = {11580}, title = {Proximity-dependent split RNA polymerases as a versatile biosensor platform}, number = {PATENT}, month = {Feb}, year = {2024}, abstract = {A proximity dependent split T7 RNAP (RNA polymerase) sensor using continuous molecular evolution is described. The versatility of the platform is described by creating robust light and small molecule-responsive genetic sensors. The activity-responsive RNAP platform dramatically simplifies and expands genetic circuit creation, and opens new opportunities in protein engineering, synthetic biology, and bioengineering. }, url = {http://knowledge.uchicago.edu/record/11580}, }