000011112 001__ 11112 000011112 005__ 20240523043701.0 000011112 02470 $$ahttps://doi.org/10.31635/ccschem.023.202303094$$2doi 000011112 037__ $$aTEXTUAL 000011112 037__ $$bArticle 000011112 041__ $$aeng 000011112 245__ $$aChemical Approaches to Emerging Advancements in Deformable Bioelectronics: Synthesis, Device Concepts, Performance, and Applications 000011112 269__ $$a2023-08-30 000011112 336__ $$aArticle 000011112 520__ $$aThis mini review examines the current advances and future prospects of chemical approaches in deformable bioelectronics, emphasizing their transformative potential in healthcare and other sectors. The mini review outlines novel fabrication strategies that rely on chemical principles to create adaptable, comfortable, and durable bioelectronic devices that are capable of seamlessly integrating into the dynamic biological environment. The discussion also extends to the integration of innovative device concepts that enhance the outcomes in both sensing and modulation functionalities. Performance-enhancing strategies that use chemistry to refine the sensitivity and precision of these devices are also highlighted. Moreover, the mini review explores the emerging applications of chemically enhanced bioelectronic devices in healthcare, reflecting the potential of this field to revolutionize patient care and improve health monitoring. In the outlook section, this mini review investigates the promising future of transient and living bioelectronics, emphasizing the pivotal role of chemical approaches in their development. It additionally covers the potential of chemical techniques in powering bioelectronic devices using biological systems and discusses the prospective applications of chemically synthesized bioelectronic devices outside of healthcare. While the field has made substantial progress, this mini review also identifies challenges that must be addressed, thus underlining the necessity for continued research and chemical innovation in bioelectronics. 000011112 536__ $$oNational Science Foundation$$cNSF DMR-2105321 000011112 536__ $$oNational Science Foundation$$cNSF CBET-2128140 000011112 540__ $$a<p>© 2023 Chinese Chemical Society</p> <p>This article was published under the terms of the <a href="https://creativecommons.org/licenses/by-nc/3.0/" target="_blank">Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC 3.0)</a>.</p> 000011112 542__ $$fCC BY-NC 000011112 593__ $$aThis article has been published in <i>CCS Chemistry</i> 2023; "Chemical Approaches to Emerging Advancements in Deformable Bioelectronics: Synthesis, Device Concepts, Performance, and Applications" is available online at <a href="https://doi.org/10.31635/ccschem.023.202303094" target="_blank">https://doi.org/10.31635/ccschem.023.202303094</a>. 000011112 6531_ $$adeformable bioelectronics 000011112 6531_ $$ahydrogels 000011112 6531_ $$abiointerfaces 000011112 6531_ $$asensing 000011112 6531_ $$amodulation 000011112 6531_ $$asemiconductors 000011112 6531_ $$acells and tissues 000011112 690__ $$aPhysical Sciences Division 000011112 691__ $$aChemistry 000011112 692__ $$aInstitute for Biophysical Dynamics 000011112 692__ $$aJames Franck Institute 000011112 7001_ $$aAbu-Halimah, Jj$$uUniversity of Chicago 000011112 7001_ $$aMajmudar, Aman$$uUniversity of Chicago 000011112 7001_ $$aTian, Bozhi$$uUniversity of Chicago 000011112 773__ $$tCCS Chemistry 000011112 8564_ $$98d743194-fa72-4e20-ad8d-047c8dc01a39$$s15290216$$uhttps://knowledge.uchicago.edu/record/11112/files/Chemical-Approaches-to-Emerging-Advancements-in-Deformable-Bioelectronics.pdf$$ePublic 000011112 908__ $$aI agree 000011112 909CO $$ooai:uchicago.tind.io:11112$$pGLOBAL_SET 000011112 983__ $$aArticle