@article{TEXTUAL,
      recid = {10179},
      author = {Dooley, Keven D. and Bergelson, Joy},
      title = {Richness and density jointly determine context dependence  in bacterial interactions},
      journal = {iScience},
      address = {2023-12-07},
      number = {TEXTUAL},
      abstract = {Pairwise interactions are often used to predict features  of complex microbial communities due to the challenge of  measuring multi-species interactions in high dimensional  contexts. This assumes that interactions are unaffected by  community context. Here, we used synthetic bacterial  communities to investigate that assumption by observing how  interactions varied across contexts. Interactions were most  often weakly negative and showed a phylogenetic signal  among genera. Community richness and total density emerged  as strong predictors of interaction strength and  contributed to an attenuation of interactions as richness  increased. Population level and per-capita measures of  interactions both displayed such attenuation, suggesting  factors beyond systematic changes in population size were  involved; namely, changes to the interactions themselves.  Nevertheless, pairwise interactions retained some  explanatory power across contexts, provided those contexts  were not substantially divergent in richness. These results  suggest that understanding the emergent properties of  microbial interactions can improve our ability to predict  the features of microbial communities.},
      url = {http://knowledge.uchicago.edu/record/10179},
}