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1.
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The appendix is a secondary lymphoid organ that sits at the junction between the small and large intestine. Housing both dense lymphoid tissue and its own microbiome, [...]
2025-03 |
Immunology |
Dissertation |
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2.
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Vertebrates differ over 100,000-fold in responses to pro-inflammatory agonists such as bacterial lipopolysaccharide (LPS), complicating use of animal models to study huma [...]
28 December 2024 |
Human Genetics[...] |
Article |
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3.
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Volume-regulated anion channels (VRACs) are heteromeric complexes formed by proteins of the leucine-rich repeat-containing 8 (LRRC8) family. LRRC8A (also known as SWELL1) [...]
22 December 2024 |
Biochemistry and Molecular Biology[...] |
Article |
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4.
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Provided herein are anti-neuraminidase agents useful for neutralization of influenza virus infection, and methods of use and manufacture thereof. In particular, compositi [...]
05 November 2024 |
Immunology |
Patent |
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5.
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Provided herein are anti-neuraminidase agents useful for neutralization of influenza virus infection, and methods of use and manufacture thereof. In particular, compositi [...]
03 September 2024 |
Immunology |
Patent |
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6.
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Provided herein are anti-neuraminidase agents useful for neutralization of influenza virus infection, and methods of use and manufacture thereof. In particular, compositi [...]
03 September 2024 |
Immunology |
Patent |
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7.
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Celiac disease (CeD) is a complex intestinal inflammatory disorder that is triggered by dietary gluten and develops in genetically susceptible individuals expressing [...]
2024-12 |
Immunology |
Dissertation |
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8.
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The determination of the cancer prognosis is paramount for patients and medical personnel so that they can devise treatment strategies. Transcriptional-based signatures a [...]
27 September 2024 |
Immunology; Medicine |
Article |
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9.
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Immune stimulating agents like Toll-like receptor 7 (TLR7) agonists induce potent antitumor immunity but are limited in their therapeutic window due to off-target immune [...]
07 October 2022 |
Ben May Department for Cancer Research; Cancer Biology; Immunology |
Article |
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10.
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Background: Toxoplasmosis is potentially avoidable, treatable, and curable by simple and direct preventive measures. Knowledge, attitudes, and practices (KAP) assessme [...]
10 August 2024 |
Immunology; Ophthalmology and Visual Science; Pediatrics |
Article |
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11.
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Tissue lymphatics are crucial for fluid homeostasis and immunosurveillance. We asked whether the lymphatics are adapted to the organ in which they reside, such as along t [...]
2024-08 |
Immunology |
Dissertation |
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12.
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The mucosal barrier of the gastrointestinal tract is essential for maintaining tolerance to the commensal microbiota and protecting the host from pathogenic infections. A [...]
2024-08 |
Immunology |
Dissertation |
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13.
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The innate immune system is the first line of defense against pathogens and immunological threats. By engaging a large cassette of pattern recognition receptors (PRRs) t [...]
2024-08 |
Immunology |
Dissertation |
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14.
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Classical NK cells are the prototypical type 1 innate lymphocytes mounting cytolytic and IFNγ responses to intracellular pathogens and tumors. A similar but distinc [...]
2024-08 |
Immunology |
Dissertation |
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15.
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Checkpoint blockade immunotherapy (CBI) is a cornerstone of modern cancer treatment, but efficacy is not universal, partly due to a wide variation in baseline immune cell [...]
2024-06 |
Immunology |
Dissertation |
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16.
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Allergic asthma is an increasing burden in industrialized countries, where treatments are limited to treating symptoms rather than root causes. In recent years, the use o [...]
2024-06 |
Immunology |
Dissertation |
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17.
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This study aimed to elucidate the complex interplay between microbiota diversity, microbial-derived signals, and alloimmune responses in the context of allograft rejectio [...]
2024-06 |
Immunology |
Dissertation |
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18.
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Host-microbiota-pathogen interactions play a key role in determining survival from lethal bacterial infection leading to sepsis. Here we demonstrate that western diet, h [...]
2024-06 |
Immunology |
Dissertation |
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19.
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T cell Acute Lymphoblastic Leukemia (T-ALL) is a highly heterogeneous hematological malignancy resulting from the transformation of immature thymocytes during their devel [...]
2024-06 |
Immunology |
Dissertation |
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20.
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Antituberculosis drugs, mostly developed over 60 years ago, combined with a poorly effective vaccine, have failed to eradicate tuberculosis. More worryingly, multiresista [...]
29 April 2024 |
Genetics, Genomics, and Systems Biology; Immunology; Medicine |
Article |
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21.
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Commensal microbes have the capacity to affect development and severity of autoimmune diseases. Germ-free (GF) animals have proven to be a fine tool to obtain definitive [...]
08 May 2024 |
Cancer Biology; Immunology; Microbiology; Pathology |
Article |
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22.
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RNA velocity estimation is a potentially powerful tool to reveal the directionality of transcriptional changes in single-cell RNA-sequencing data, but it lacks accuracy, [...]
26 April 2024 |
Chemistry; Immunology; Medicine |
Article |
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23.
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Bacillus Calmette–Guérin (BCG) vaccination induces memory characteristics in innate immune cells and their progenitors, a process called trained immunity mediated by e [...]
11 March 2024 |
Immunology; Medicine |
Article |
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24.
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Humans exhibit considerable variability in their immune responses to the same immune challenges. Such variation is widespread and affects individual and population-level [...]
05 April 2024 |
Genetics, Genomics, and Systems Biology; Human Genetics; Immunology; Medicine |
Article |
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25.
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Previously, we showed that a massively parallel reporter assay, mSTARR-seq, could be used to simultaneously test for both enhancer-like activity and DNA methylation-depen [...]
26 February 2024 |
Human Genetics; Immunology; Medicine |
Article |
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