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1.
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Bacillus Calmette–Guérin (BCG) vaccination induces memory characteristics in innate immune cells and their progenitors, a process called trained immunity mediated by e [...]
11 March 2024 |
Immunology; Medicine |
Article |
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2.
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Humans exhibit considerable variability in their immune responses to the same immune challenges. Such variation is widespread and affects individual and population-level [...]
05 April 2024 |
Genetics, Genomics, and Systems Biology; Human Genetics; Immunology; Medicine |
Article |
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3.
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Previously, we showed that a massively parallel reporter assay, mSTARR-seq, could be used to simultaneously test for both enhancer-like activity and DNA methylation-depen [...]
26 February 2024 |
Human Genetics; Immunology; Medicine |
Article |
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4.
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The vast diversity of mammalian adaptive antigen receptors allows for robust and efficient immune responses against a wide number of pathogens. The antigen receptor reper [...]
04 March 2024 |
Genetics, Genomics, and Systems Biology; Immunology; Microbiology |
Article |
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5.
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Demand-adjusted and cell type specific rates of protein synthesis represent an important safeguard for fate and function of long-term hematopoietic stem cells. Here, we i [...]
29 February 2024 |
Immunology |
Article |
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6.
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The revolutionizing efficacy of recombinant human bone morphogenetic protein (rhBMP-2) for clinical spinal fusion is hindered by safety issues associated with the high do [...]
11 June 2021 |
Cancer Biology; Immunology; Radiology |
Article |
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7.
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Enhancing the therapeutic efficacy of drugs for inflammatory diseases is of high demand. One possible approach is targeting drugs to the extracellular matrix of the infla [...]
06 November 2019 |
Immunology |
Article |
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8.
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Although a clinical breakthrough for cancer treatment, it remains that a minority of patients respond to checkpoint inhibitor (CPI) immunotherapy. The composition of tumo [...]
11 December 2019 |
Ben May Department for Cancer Research; Immunology |
Article |
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9.
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<p>Background: Primary Toxoplasma gondii infection during pregnancy can be transmitted to the fetus. At birth, infected infants may have intracranial calcification, [...]
04 June 2008 |
Immunology; Medicine; Ophthalmology and Visual Science; Pediatrics |
Article |
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10.
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Embodiments concern methods and composition related to anergic T-cells in patients, such as cancer patients.
13 May 2021 |
Immunology; Medicine |
Patent |
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11.
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<p>Molecular pathways regulating rapid proliferation and persistence are fundamental for pathogens but are not elucidated fully in <em>Toxoplasma gondii.</ [...]
22 November 2010 |
Immunology; Pathology; Pediatrics; Surgery |
Article |
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12.
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<p>Background: Id3 is a dominant antagonist of E protein transcription factor activity that is induced by signals emanating from the αβ and γδ T cell receptor ( [...]
19 February 2010 |
Biochemistry and Molecular Biology; Immunology; Pathology |
Article |
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13.
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<p><em>Candida albicans</em> is an opportunistic pathogen that proliferates in the intestinal tract of critically ill patients where it continues to be [...]
13 January 2012 |
Immunology; Microbiology; Surgery |
Article |
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14.
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<p>H3N2 influenza viruses have now circulated in the human population for 43 years since the pandemic of 1968, accumulating sequence changes in the hemagglutinin (H [...]
25 July 2012 |
Immunology |
Article |
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15.
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<p>Engagement of the B cell antigen receptor initiates two concurrent processes, signaling and receptor internalization. While both are required for normal humoral [...]
30 May 2006 |
Chemistry; Immunology; Medicine |
Article |
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16.
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Tissue resident lymphocytes are critical sentinels of tissue homeostasis, capable of producing rapid memory responses upon detection of pathogens or stress. In humans, T [...]
2023-12 |
Immunology |
Dissertation |
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17.
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Cancer immunotherapy is moving toward combination regimens with agents of complementary mechanisms of action to achieve more frequent and robust efficacy. However, compar [...]
29 November 2023 |
Ben May Department for Cancer Research; Cancer Biology; Immunology |
Article |
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18.
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Antibodies are critical components of adaptive immunity, binding with high affinity to pathogenic epitopes. Antibodies undergo rigorous selection to achieve this high aff [...]
10 November 2020 |
Biochemistry and Molecular Biology; Biophysical Sciences; Immunology; Medicine; Pathology |
Article |
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19.
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Breakdown of B cell tolerance is a cardinal feature of systemic lupus erythematosus (SLE). Increased numbers of autoreactive mature naïve B cells have been described in [...]
07 May 2015 |
Immunology; Medicine |
Article |
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20.
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Non-healing wounds have a negative impact on quality of life and account for many cases of amputation and even early death among patients. Diabetic patients are the predo [...]
11 September 2023 |
Cancer Biology; Immunology; Molecular Metabolism and Nutrition |
Article |
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21.
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Compositions comprising NKT cell agonist compounds and a physiologically acceptable vehicle are provided. Methods of stimulating an NKT cell and enhancing an immune respo [...]
24 April 2008 |
Immunology; Pathology; Medicine |
Patent |
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22.
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Compositions comprising NKT cell agonist compounds and a physiologically acceptable vehicle are provided. Methods of stimulating an NKT cell and enhancing an immune respo [...]
14 September 2010 |
Immunology; Pathology; Medicine |
Patent |
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23.
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Compositions comprising NKT cell agonist compounds and a physiologically acceptable vehicle are provided. Methods of stimulating an NKT cell and enhancing an immune respo [...]
03 February 2011 |
Immunology; Pathology; Medicine |
Patent |
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24.
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Compositions comprising NKT cell agonist compounds and a physiologically acceptable vehicle are provided. Methods of stimulating an NKT cell and enhancing an immune respo [...]
13 January 2015 |
Immunology; Pathology; Medicine |
Patent |
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25.
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This invention relates to galactosylceramide compounds.
02 June 2015 |
Immunology; Pathology; Medicine |
Patent |
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