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Gwen Knapp Center for Lupus and Immunology Research

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1.	Multiple Files zhao_2023_oi_230131_1679406279.72266 Racial Disparities in Pathological Complete Response among Patients Receiving Neoadjuvant Chemotherapy for Early-Stage Breast Cancer Zhao, Fangyuan ; Miyashita, Minoru ; Hattori, Masaya ; Yoshimatsu, Toshio ; Howard, Frederic[...] Importance: Among patients with breast cancer, inconsistent findings have been published on racial disparities in achieving pathologic complete response (pCR) after ne [...] 30 March 2023 \| Medicine; Public Health Sciences; Surgery \| Article \| Detailed record - Similar records
2.	Multiple Files sciadv.adf8156 The ion transporter Na<sup>+</sup>-K<sup>+</sup>-ATPase enables pathological B cell survival in the kidney microenvironment of lupus nephritis Chernova, Irene ; Song, Wenzhi ; Steach, Holly ; Hafez, Omeed ; Al Souz, Jafar ; Chen, Ping-Min ; [...] The kidney is a comparatively hostile microenvironment characterized by highsodium concentrations; however, lymphocytes infiltrate and survive therein in autoimmune disea [...] 01 February 2023 \| Medicine; Pathology \| Article \| Detailed record - Similar records
3.	Multiple Files journal.pgen.1002079 Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility Zhao, Jian ; Wu, Hui ; Khosravi, Melanie ; Cui, Huijuan ; Qian, Xiaoxia ; Kelly, Jennifer A. ; Kau[...] Systemic lupus erythematosus (SLE), a complex polygenic autoimmune disease, is associated with increased complement activation. Variants of genes encoding complement regu [...] 26 May 2011 \| Gwen Knapp Center for Lupus and Immunology Research \| Article \| Detailed record - Similar records
4.	Multiple Files journal.ppat.1004204 Biogenesis of Influenza A Virus Hemagglutinin Cross-Protective Stem Epitopes Magadán, Javier G. ; Altman, Meghan O. ; Ince, William L. ; Hickman, Heather D. ; Stevens, [...] Antigenic variation in the globular domain of influenza A virus (IAV) hemagglutinin (HA) precludes effective immunity to this major human pathogen. Although the HA ste [...] 12 June 2014 \| Medicine \| Article \| Detailed record - Similar records
5.	Multiple Files journal.pone.0029126 Linkage of Type I Interferon Activity and TNF-Alpha Levels in Serum with Sarcoidosis Manifestations and Ancestry Sweiss, Nadera J. ; Zhang, Wei ; Franek, Beverly S. ; Kariuki, Silvia N. ; Moller, David R. ; P[...] Background: Both type I interferon (IFN), also known as IFN-α and tumor necrosis factor alpha (TNF-α) have been implicated in the pathogenesis of sarcoidosis. We inv [...] 14 December 2011 \| Medicine \| Article \| Detailed record - Similar records
6.	Multiple Files journal.pone.0089792 Recruitment of Cbl-b to B Cell Antigen Receptor Couples Antigen Recognition to Toll-Like Receptor 9 Activation in Late Endosomes Veselits, Margaret ; Tanaka, Azusa ; Lipkowitz, Stanley ; O'Neill, Shannon ; Sciammas, Roger ; [...] Casitas B-lineage lymphoma-b (Cbl-b) is a ubiquitin ligase (E3) that modulates signaling by tagging molecules for degradation. It is a complex protein with multiple do [...] 20 March 2014 \| Medicine \| Article \| Detailed record - Similar records
7.	PDF Generalizations-of-the-Jaccard-index Generalizations of the Jaccard index and Sørensen index for assessing agreement across multiple readers in object detection and instance segmenta[...] Durkee, Madeleine S. ; Lleras, Kyle ; Drukker, Karen ; Ai, Junting ; Cao, Thao ; Casella, Gabri[...] Significance: Manual annotations are necessary for training supervised learning algorithms for object detection and instance segmentation. These manual annotations are [...] 14 December 2023 \| Medical Physics; Medicine; Radiology \| Article \| Detailed record - Similar records
8.	Multiple Files saadalla-et-al-2018-mast-cells-promote-small-bowel-cancer-in-a-tumor-stage-specific-and-cytokine-dependent-manner Mast cells promote small bowel cancer in a tumor stage-specific and cytokine-dependent manner Saadalla, Abdulrahman M. ; Osman, Abu ; Gurish, Michael F. ; Dennis, Kristen L. ; Blatner, N[...] Mast cells (MCs) are tissue resident sentinels that mature and orchestrate inflammation in response to infection and allergy. While they are also frequently observed in t [...] 02 February 2018 \| Medicine \| Article \| Detailed record - Similar records
9.	Multiple Files journal.pone.0125618 High Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination Kaur, Kaval ; Zheng, Nai-Ying ; Smith, Kenneth ; Huang, Min ; Li, Lie ; Pauli, Noel T. ; Henry Dun[...] Breakdown of B cell tolerance is a cardinal feature of systemic lupus erythematosus (SLE). Increased numbers of autoreactive mature naïve B cells have been described in [...] 07 May 2015 \| Immunology; Medicine \| Article \| Detailed record - Similar records
10.	Multiple Files journal.pone.0139695 Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins Zhong, Nan ; Loppnau, Peter ; Seitova, Alma ; Ravichandran, Mani ; Fenner, Maria ; Jain, Harshi[...] We developed and optimized a high-throughput project workflow to generate renewable recombinant antibodies to human proteins involved in epigenetic signalling. Three diff [...] 05 October 2015 \| Biochemistry and Molecular Biology \| Article \| Detailed record - Similar records
11.	Multiple Files journal.ppat.1005815 Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design Jardine, Joseph G. ; Sok, Devin ; Julien, Jean-Philippe ; Briney, Bryan ; Sarkar, Anita ; Liang[...] An optimal HIV vaccine should induce broadly neutralizing antibodies (bnAbs) that neutralize diverse viral strains and subtypes. However, potent bnAbs develop in only a s [...] 25 August 2016 \| Medicine \| Article \| Detailed record - Similar records
12.	Multiple Files journal.ppat.1008409 Characterizing Emerging Canine H3 Influenza Viruses Martinez-Sobrido, Luis ; Blanco-Lobo, Pilar ; Rodriguez, Laura ; Fitzgerald, Theresa ; Zhang[...] The continual emergence of novel influenza A strains from non-human hosts requires constant vigilance and the need for ongoing research to identify strains that may pose [...] 14 April 2020 \| Medicine; Immunology \| Article \| Detailed record - Similar records
13.	Multiple Files journal.ppat.1009288 Extrafollicular CD4 T cell-derived IL-10 functions rapidly and transiently to support anti-<i>Plasmodium</i> humoral immunity Surette, Fionna A. ; Guthmiller, Jenna J. ; Li, Lei ; Sturtz, Alexandria J. ; Vijay, Rahul ; Po[...] Immunity against malaria depends on germinal center (GC)-derived antibody responses that are orchestrated by T follicular helper (TFH) cells. Emerging data show that t [...] 02 February 2021 \| Immunology; Medicine \| Article \| Detailed record - Similar records

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