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1.
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The cellular source of positive signals that reinvigorate T cells within the tumor microenvironment (TME) for the therapeutic efficacy of programmed death-1 (PD-1)/p [...]
23 April 2024 |
Medicine; Pathology |
Article |
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2.
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<p>Background: Frailty is a predictor of poor outcomes following many types of operations. We measured thoracic surgeons' accuracy in assessing patient frailty usin [...]
03 June 2014 |
Anesthesia and Critical Care; Medicine; Public Health Sciences; Surgery |
Article |
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3.
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Particulate matter (PM) air pollution causes cardiopulmonary mortality via macrophage-driven lung inflammation; however, the mechanisms are incompletely understood. RNA-s [...]
07 April 2020 |
Medicine |
Article |
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4.
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Membrane proteins with multiple transmembrane domains play critical roles in cell physiology, but little is known about the machinery coordinating their biogenesis at the [...]
21 August 2020 |
Biochemistry and Molecular Biology; Molecular Genetics and Cell Biology |
Article |
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5.
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Limiting CD4 + T cell responses is important to prevent solid organ transplant rejection. In a mouse model of costimulation blockade-dependent cardiac allograft [...]
26 September 2022 |
Medicine; Surgery |
Article |
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6.
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Synthesis of triiodothyronine (T3) in the hypothalamus induces marked seasonal neuromorphology changes across taxa. How species-specific responses to T3 signaling in the [...]
12 June 2019 |
Pediatrics; Psychology |
Article |
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7.
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<p>Meta-analysis of gene expression array databases has the potential to reveal information about gene function. The identification of gene-gene interactions may be [...]
05 March 2014 |
Medicine |
Article |
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8.
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Whole exome sequencing has facilitated the discovery of causal genetic variants associated with human diseases at deep coverage and low cost. In particular, the detection [...]
13 August 2015 |
Pediatrics |
Article |
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9.
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Kawasaki disease (KD) or Kawasaki syndrome is known as a vasculitis of small to medium-sized vessels, and coronary arteries are predominantly involved in childhood. Gener [...]
12 May 2016 |
Center for Research Informatics |
Article |
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10.
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Human papillomaviruses (HPVs) are epithelial tropic viruses that link their productive life cycles to the differentiation of infected host keratinocytes. A subset of the [...]
07 July 2016 |
Center for Research Informatics |
Article |
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11.
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<p>Understanding the genetic architecture of gene expression traits is key to elucidating the underlying mechanisms of complex traits. Here, for the first time, we [...]
11 November 2016 |
Medicine |
Article |
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12.
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<p>Purpose: Retinopathy of prematurity (ROP) is the leading cause of preventable childhood blindness worldwide. Although interventions such as anti-VEGF and laser h [...]
10 July 2023 |
Medicine; Ophthalmology and Visual Science |
Article |
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13.
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Improved systems for detection of measurable residual disease (MRD) in acute myeloid leukemia (AML) are urgently needed, however attempts to utilize broad-scale next-gene [...]
28 October 2019 |
Family Medicine; Genetics, Genomics, and Systems Biology; Pathology |
Article |
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14.
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Exosomes are extracellular vesicles (EVs) of ~20–200 nm diameter that shuttle DNAs, RNAs, proteins and other biomolecules between cells. The large number of biomolecule [...]
02 March 2020 |
Pathology |
Article |
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15.
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The mechanisms that underlie the timing of labor in humans are largely unknown. In most pregnancies, labor is initiated at term (≥ 37 weeks gestation), but in a signi [...]
16 May 2023 |
Human Genetics; Obstetrics and Gynecology |
Article |
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16.
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Immune genes have evolved to maintain exceptional diversity, offering robust defense against pathogens. We performed genomic assembly to examine immune gene variation in [...]
13 May 2023 |
Medicine; Pediatrics |
Article |
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17.
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Inorganic arsenic is highly toxic and carcinogenic to humans. Exposed individuals vary in their ability to metabolize arsenic, and variability in arsenic metabolism effic [...]
20 January 2023 |
Human Genetics; Medicine; Public Health Sciences |
Article |
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18.
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The early life microbiome plays critical roles in host development, shaping long-term outcomes including brain functioning. It is not known which initial infant colonizer [...]
28 November 2021 |
Medicine; Pediatrics |
Article |
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